26/02/2020

Postdoctoral position in constitutional MLH1 epimutations

This job offer has expired


  • ORGANISATION/COMPANY
    Bellvitge Biomedical Research Institute (IDIBELL)
  • RESEARCH FIELD
    Biological sciencesBiology
  • RESEARCHER PROFILE
    First Stage Researcher (R1)
  • APPLICATION DEADLINE
    13/03/2020 23:00 - Europe/Brussels
  • LOCATION
    Spain › L Hospitalet de Llobregat (Barcelona)
  • TYPE OF CONTRACT
    Other
  • JOB STATUS
    Other

We are seeking for a post-doctoral candidate that will develop a project aimed at elucidating the causal mechanism of constitutional MLH1 epimutations. The position is available immediately.

After the extensive molecular characterization of our series of MLH1 epimutations (PMID 22763379, 30283143; 31779681), our aim is to elucidate the molecular mechanisms underlying constitutional MLH1 methylation. To address this issue the candidate will undertake a comprehensive study of the genomes and epigenomes of a unique set of cancer-affected families with MLH1 epimutations using modern techniques capable of detecting and resolving complex genetic and epigenetic alterations.

Benefits

HOST GROUP

The candidate will have the opportunity to initiate and conduct research within the Hereditary Cancer Group at IDIBELL (www.idibell.cat/en/content/hereditary-cancer) under the supervision of Dr. Gabriel Capellá. The project will be carried out in collaboration with Dr. Megan Hitchins (Cedars-Sinai, USA) and Dr. Lorenzo Pasquali (Institut Carreras, Spain).

 

The overarching goal of the Hereditary Cancer Group at IDIBELL is to gain insight into the molecular basis of hereditary cancer, to personalize risk assessment to patients and relatives, as well as to individualize management regarding follow-up, treatment and prophylactic measures. Our multidisciplinary group includes basic researchers, clinicians, bioinformaticians, genetic counselors in familial cancer and laboratory technicians, facilitating fully comprehensive studies, data analysis, access to the patients and samples, and the translation of the obtained results to the clinics and genetic counseling.

Successful candidates will join a dynamic, young and well-equipped research group with strong interactions and multidisciplinary research. The group offers a stimulating research atmosphere and an environment in which collaboration and exchange of ideas and techniques is actively encouraged with a strong commitment to research which provides a lively and stimulating environment for young talents.

INSTITUTION

IDIBELL is one of the most dynamic health research institutes in Spain with more than 800 researchers in the fields of basic, clinical and epidemiological research striving to attain significant improvements in human health. Research is structured into 3 thematic areas (cancer, neurosciences and translational medicine) with a total of 9 research programs. IDIBELL has all of the facilities, infrastructure and equipment necessary to promote and support innovative, cutting edge research.

Selection process

To apply, please send a cover letter containing a statement of research interest and experience, a CV and names and contact information for three researchers that are familiar with you and with your work to Marta Pineda (mpineda@iconcologia.net) before 13th March 2020.

Offer Requirements

  • REQUIRED EDUCATION LEVEL
    Biological sciences: PhD or equivalent
  • REQUIRED LANGUAGES
    ENGLISH: Excellent

Skills/Qualifications

  • Proven experience in human genetics, epigenetics and molecular biology (including cancer biology).
  • Any participation in research projects, co-authorship in publications and mobility experience will be considered as a valuable contribution.
  • English proficiency.
  • Good communication skills.
  • High motivation and ability to be involved in a multidisciplinary team.

Map Information

Job Work Location Personal Assistance locations
Work location(s)
1 position(s) available at
Bellvitge Biomedical Research Institute (IDIBELL)
Spain
Barcelona
L Hospitalet de Llobregat (Barcelona)
08908
Av. Gran Via de l Hospitalet, 199-203

EURAXESS offer ID: 498021

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